Synopsis:

Hot but estranged brothers Sam (Jared Padalecki) and Dean (Jensen Ackles) Winchester go on the road in a vintage muscle car, searching out ghouls, ghosts, demons and Daddy, to a soundtrack of 80's hair bands.

Season 1:

Sam is brought back into the Winchester family business (monster killing) after the demon-related death of his pretty blonde girlfriend. With his hunting-expert father missing, Sam must reluctantly rely on his snarky brother, Dean, in order to track down the demon responsible. They find Dad, who tells them to kill the accursed, girlfriend- (and Mom-) burning "Yellow-eyed" demon with a magic gun. Also, Sam's psychic now!

Season 2:

With Dad dead, but the demon still at large, Sam and Dean are on the road once more, destroying random beasties while trying to figure out what connection lies between Yellow Eyes, Sam, and a bunch of his super-power-having contemporaries. New friends are met, new enemies created, and the gates of Hell are opened. And -- oh, dear! Dean has only a year to live.

Season 3:

The search for demon-contract loopholes takes the brothers into some murky territory, making alliances with bad girls like Ruby the demon (Katie Cassidy) and Bela the thief (Lauren Cohan). But in the end, their attempts at reneging prove futile, they fail to kill the powerful (so creepy) child-demon Lilith (Sierra McCormick), and Dean is dragged off to Hell. 

Season 4:

Dean is back from Hell! What a thoroughly unexpected development. How, though? And, why? Well... it's 'cause of angels, obviously. The legions of Heaven are gearing up for a showdown with the minions of Hell, and they need Dean in the mix. Sam is also important in the coming war; he becomes addicted to drinking demon blood and ends up raising Satan. The Winchesters are both consumed by the ensuing explosion...

Season 5 (Episodes 1-14):

... oh, not to worry. It's okay. God saved them. But with Sam and Dean still first round draft picks for the opposing sides, they must battle their inner demons, as well as many literal ones, in order to save the world from the already-in-progress Apocalypse. With the help of their ex-communicated angel buddy, Castiel (Misha Collins), the boys fight the good fight -- and each other -- in what may well be the end for the entire human race. What will happen next? Can the Winchesters save the world? Only time will tell...

05.15 - "Dead Men Don't Wear Plaid"

Zombies.

05.16 - "Dark Side of the Moon"

Heaven is Disneyland and God is a dick.

05.17 - "99 Problems"

Damn, Dean. Seriously… damn.

05.18 - "Point of No Return"

Whew!

05.19 - "Hammer of the Gods"

It's a god off!

05.20 - "Devil You Know"

Demons in business suits make an impression.

05.21 - "Two Minutes to Midnight"

05.22 - "Swan Song"

!!!!!!!!!!!!!!!!!!!!!